Systems and Methods for Detecting CRISPR-mediated Residues Within Methylated Patterns of Genome Using a Convolutional Neural Network

A system, method, and computer-readable medium for detecting a CRISPR-edited genome are disclosed. Certain embodiments of the system may include one or more processors configured to: receive sequence data of a genome; generate an image representation of the sequenced data, the image being a plot of methylation variations as a function of methylation locations in the genome; apply the generated image representation to a trained convoluted neural network (CNN); generate, using the CNN, a score indicative of a probability that the genome was CRISPR-edited; and determine, based on the score, whether the genome contains a CRISPR-edited methylation region. A corresponding method and computer-readable medium are also provided.

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