Glycelles for Pathogen Capture
When mixed under sterile conditions according to patented methods, glycoproteins and oils associate to form transparent, film-coated spheres or “glycelles,” which remain stable at room temperature for months. When damp, their sugar coating is slippery, so glycelles do not stick to solid surfaces or extraneous particulate matter. However, when sprayed onto dry paper or cloth containing cellulose, glycelles wrap around the fibers and cannot be readily removed by detergents. When rehydrated, sugar chains on the exterior surface radiate from the film sheath and bind to complementary lectins of pathogens and biotoxins with which they come into contact. MITRE has demonstrated, using a fluorescent plant lectin, that damp, glycelle-treated wipes can remove sticky biotoxins from solid surfaces without leaving a trace behind.
To discuss licensing or collaboration activities, please contact MITRE's TTO .